The primary hyperoxaluria treatment market share is anticipated to reach a valuation of US$ 18 million globally in 2023, and it is anticipated to grow at a compound annual growth rate (CAGR) of 8.6% to reach US$ 41.07 million during the forecast period of 2023 to 2033. Historically, the market for primary hyperoxaluria treatment grew at a compound annual growth rate (CAGR) of 5.2% from 2018 to 2022.

The U.S. Food and Drug Administration (FDA) authorised Lumasiran in 2020, making it one of the most promising treatments for primary hyperoxaluria. Lumasiran helps lower the body's oxalate production by focusing on the underlying genetic basis of primary hyperoxaluria. Promising outcomes from Lumasiran's clinical trials include individuals having marked drops in urine oxalate levels and a lower risk of kidney stones.

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In addition to Lumasiran, there are several other treatments in development for primary hyperoxaluria. These include gene therapy approaches that aim to correct the underlying genetic mutation that causes the condition. There is also ongoing research into the use of existing drugs, such as potassium citrate, in the treatment of primary hyperoxaluria.

The market for primary hyperoxaluria treatment is expected to grow rapidly in the coming years as more therapies become available. This growth is being driven by a number of factors, including increasing awareness and diagnosis of the condition, the development of new treatments, and favorable reimbursement policies. North America is currently the largest market for primary hyperoxaluria treatment, accounting for a significant share of global sales. This is due in part to the high prevalence of primary hyperoxaluria in the region, as well as the strong healthcare infrastructure and favorable reimbursement policies.

Key Takeaways from the Market Study

• From 2018 to 2022, the primary hyperoxaluria treatment market grew at a CAGR of 5.2%.
• The global primary hyperoxaluria treatment market is expected to grow with an 8.6% CAGR from 2023 to 2033.
• As of 2033, the primary hyperoxaluria treatment market is expected to reach US$ 41.07 million.
• According to the FMI analysis, the hospital pharmacies segment accounts for the largest market share.
• North America is expected to possess a 40% market share for the Primary Hyperoxaluria Treatment market.
• The East & South Asia market is predicted to increase significantly throughout the forecast period, with a share of 20% during the forecast period.

“A series of international level collaborations involving healthcare stakeholders across various institutional settings are fueling further clinical trials and research studies dedicated to discovering primary hyperoxaluria treatment,” says an FMI analyst

Market Competition

Key players in the market include companies such as Competition Deep Dive,  Alnylum Pharma, OxThera, Dicerna Pharmaceuticals, Inc., Allena Pharmaceuticals, Biocodex, Tecoland Corporation, Zhejiang Tianxin Pharmaceutical Co., Takeda Pharmaceuticals, Wuxi Further Pharmaceutical Co Ltd, Genentech, along with healthcare providers and technology companies among other global players.

• In 2020, the United States Food and Drug Administration (FDA) gave the green light to Oxlumo (lumasiran) as the initial treatment for primary hyperoxaluria type 1 (PH1), a rare hereditary disorder. This groundbreaking approval is the culmination of the work of specialists and community members coordinated by the Oxalosis & Hyperoxaluria Foundation and the Kidney Health Initiative.
• The approval of Oxlumo was a result of input from patients, treating physicians, experts, and sponsors at a patient-focused drug development meeting and through other collaborative efforts. Oxlumo’s function is to reduce the production of oxalate in patients with PH1. The drug was evaluated in two separate trials in PH1 patients: a randomized, placebo-controlled trial in patients aged six years and older, and an open-label study in patients under six years old. The patients ranged in age from four months to 61 years at the start of treatment.

More Insights Available

FMI, in its new offering, presents an unbiased analysis of the global Primary Hyperoxaluria Treatment market, presenting historical analysis from 2018 to 2022 and forecast statistics for the period of 2023 to 2033.

The study reveals essential insights on the basis of type (type 1, type 2, and type 3), drug class (pyridoxine, potassium citrate, thiazides, and orthophosphates), route of administration (oral and intravenous), and distribution channel (hospital pharmacies, retail pharmacies, and online pharmacies) across seven major regions (North America, Latin America, Europe, South Asia, East Asia, Oceania, and Middle East & Africa).

Key Segments:

Type:

• Type 1
• Type 2
• Type 3

Drug Class:

• Pyridoxine
• Potassium Citrate
• Thiazides
• Orthophosphates

Route of Administration:

• Oral
• Intravenous

Distribution Channel:

• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies